Publications by authors named "C Hannum"
Importance: Before 2021, the US Food and Drug Administration required mifepristone to be dispensed in person, limiting access to medication abortion.
Objective: To estimate the effectiveness, acceptability, and feasibility of dispensing mifepristone for medication abortion using a mail-order pharmacy.
Design, Setting, And Participants: This prospective cohort study was conducted from January 2020 to May 2022 and included 11 clinics in 7 states (5 abortion clinics and 6 primary care sites, 4 of which were new to abortion provision).
Article Synopsis
- A study was conducted to analyze how often exposure to fetal red blood cells (fRBCs) exceeds the threshold for Rh sensitization in women undergoing induced abortions in the first trimester, addressing confusion around Rh testing guidelines.
- A total of 506 participants were examined, with blood samples collected before and after the procedure to measure fRBCs using high-throughput flow cytometry.
- The results showed that only 0.2% of participants had elevated fRBC counts post-abortion, suggesting that the risk of Rh sensitization in this context is very low.
Objective(s): To estimate the effectiveness, acceptability, and feasibility of medication abortion with mifepristone dispensed by a mail-order pharmacy after in-person clinical assessment.
Study Design: This is an interim analysis of an ongoing prospective cohort study conducted at five sites. Clinicians assessed patients in clinic and, if they were eligible for medication abortion and ≤ 63 days' gestation, electronically sent prescriptions for mifepristone 200 mg orally and misoprostol 800 mcg buccally to a mail-order pharmacy, which shipped medications for next-day delivery.
Objectives: This open-label non-inferiority study assessed efficacy of a common outpatient medical abortion regimen among people with pregnancies 64-70 days and 71-77 days of gestation.
Study Design: We defined non-inferiority by a 6% margin of method success. People with intrauterine pregnancies 64-77 days' gestational age by abdominal ultrasound seeking medical abortion at one of eight clinics and met eligibility criteria were offered participation.