Publications by authors named "C Halpin"
Article Synopsis
- Ferulic acid and p-coumaric acid are important phenolic acids found in the cell walls of grasses, playing crucial roles in health benefits, digestibility, and maintaining cell wall integrity.
- A study identified a specific gene mutation in barley that affects the levels of these acids, leading to a decrease in p-coumaric acid and an increase in ferulic acid, which alters their ratio in whole grain.
- This mutation could negatively impact grain quality traits, suggesting that targeting this gene may enhance grain quality for malting or improve phenolic acid content in whole grain foods.
Aims: The National Health Service (NHS) in England is facing extreme capacity pressures. The backbone of prostate cancer care is gonadotropin-releasing hormone agonist (GnRHa) therapy, commonly administered every month or 3 months. We estimated the cost and capacity savings associated with increased use of 6-monthly GnRHa therapy in England.
View Article and Find Full Text PDFBarley is a major cereal crop for temperate climates, and a diploid genetic model for polyploid wheat. Cereal straw biomass is an attractive source of feedstock for green technologies but lignin, a key determinant of feedstock recalcitrance, complicates bio-conversion processes. However, manipulating lignin content to improve the conversion process could negatively affect agronomic traits.
View Article and Find Full Text PDFProgrammed meiotic DNA double-strand breaks (DSBs), necessary for proper chromosomal segregation and viable gamete formation, are repaired by homologous recombination (HR) as crossovers (COs) or non-crossovers (NCOs). The mechanisms regulating the number and distribution of COs are still poorly understood. The regulator of telomere elongation helicase 1 (RTEL1) DNA helicase was previously shown to enforce the number of meiotic COs in but its function in plants has been studied only in the vegetative phase.
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