Publications by authors named "C H Schroeder"

Background And Purpose: Neoadjuvant chemoradiotherapy (NCRT) is a standard treatment option for locally advanced rectal cancer. However, there is still conflicting data about the genetic landscape and potential dynamics during and after NCRT. This study evaluated oncogenic driver mutations before NCRT and investigated corresponding resection samples after treatment.

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The widespread use of synthetic dyes has led to the release of substantial amounts of dye-contaminated wastewater, posing significant environmental and health concerns. This study focuses on the use of anodic and electrochemically activated persulfate oxidation for the degradation of organic contaminants. Specifically, the structural variations of nine dyes in the indigoid and azo families, and their impact on the efficiency of electrochemical oxidation were analysed.

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Article Synopsis
  • Encephalocraniocutaneous lipomatosis (ECCL), or Haberland syndrome, is a rare condition affecting the skin, central nervous system, and eyes, characterized by tumors and other abnormalities.
  • Key symptoms include specific skin lesions, subcutaneous lipomas, and neurological issues like intracranial lipomas and developmental delays.
  • Diagnosis primarily relies on clinical evaluation with possible genetic testing; management is multidisciplinary, focusing on symptom relief and monitoring for potential complications.
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Background: 90% of glioblastomas (GBM) relapse within two years of diagnosis. In contrast to the initial setting, there is no standard management for recurrent disease and options include hypofractionated stereotactic re-irradiation (re-mHSRT). The aims of this study were to investigate re-mHSRT practice in Swiss neuro-oncology centres.

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  • Myelomeningocele (MMC) primarily impacts low-resource regions, especially where there is no mandatory folic acid fortification, but research on its neurosurgical management is concentrated in high-income countries (HICs).
  • A systematic review revealed that while HICs account for a small percentage of global neural tube defect cases, they dominate both authorship and patient representation in the research literature, with minimal contributions from lower-income countries.
  • Findings suggest a significant disparity in MMC research output relative to disease burden, highlighting an urgent need for increased scholarly attention and resource allocation in lower-income countries where MMC cases are more prevalent.
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