The prevalence of antibiotics in wastewater poses risks to human and animal health, contributing to antimicrobial resistance. Although various antibiotic removal methods exist, microalgae-based technology presents a cost-effective and eco-friendly alternative; however, limited research on its long-term integration in semi-continuous wastewater treatment trials hinders our understanding of its potential effectiveness. This investigation explored the antibiotic removal capabilities of the microalga Auxenochlorella protothecoides in photobioreactors with synthetic wastewater under semi-continuous conditions over one month.
View Article and Find Full Text PDFNecrotizing enterocolitis (NEC) is a devastating disease of the neonatal gastrointestinal tract. Volatile organic compounds (VOCs), odoriferous compounds released as a byproduct of bacterial metabolism, can be used as a proxy for gut health. We hypothesized that patients with NEC would have different microbial profiles and elicit different VOC signatures as assessed by gas chromatography/mass spectrometry (GC/MS) or an electronic nose compared to controls.
View Article and Find Full Text PDFTemplate-directed synthesis has become a powerful methodology to access complex molecules. Noncovalent templating has been widely used in the last few decades, but less attention has been paid to covalent template-directed synthesis, despite the fact that this methodology was used for the first reported synthesis of a catenane. This review highlights the evolution of covalent templating over the last 60 years, thereby providing a toolbox for the design of efficient covalent templating processes.
View Article and Find Full Text PDFObjectives: The prevalence of low Vitamin D levels (<30 nmol/L) is about 15.7% globally. The aim of this study was to examine the prevalence of vitamin D deficiency in elderly patients with fragility fractures of the hip by estimating 25-hydroxyvitamin D levels and to assess whether low vitamin D levels at the time of admission affect functional outcomes at 3 months and mortality at 28 days and 1 year.
View Article and Find Full Text PDFBackground: Pain medicine care has expanded to encompass a wider range of conditions, necessitating updated education and training for pain specialists to utilize emerging technologies effectively. A national survey was conducted through several verified Pain organizations regarding pain physician employers' perspectives on pain medicine fellowship training and education. The survey aimed to gather insights from a diverse range of geographic locations, practice types (academic and private practice), and practice settings.
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