Publications by authors named "C H Chay"

Introduction: Older cancer survivors consistently express the need for interventions to reduce cancer-related fatigue (CRF) and maintain quality of life (QOL). Yoga is a promising treatment to address CRF and QOL. However, research comparing the efficacy of yoga for improving fatigue and QOL in older survivors (60+) vs.

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Article Synopsis
  • Treatment with covalent Bruton tyrosine kinase inhibitors (BTKi) is important for managing relapsed mantle cell lymphoma, but these treatments aren't curative and many patients still relapse.
  • Pirtobrutinib is a new, noncovalent BTKi that effectively targets both normal and mutant forms of BTK and offers continuous inhibition due to its favorable oral pharmacology.
  • A phase III study is underway to compare the effectiveness of pirtobrutinib against standard covalent BTKi treatments in patients with previously untreated mantle cell lymphoma.
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Thyroid screening is recommended during pregnancy with serum thyrotropin (TSH) as the primary test. However, since human chorionic gonadotropin, the serum hallmark of pregnancy, has TSH-like effects, the adequacy of TSH as a screening tool in this constellation requires further study. This study aimed to evaluate the relationship between TSH and thyroid hormones during pregnancy in order to determine if TSH is an adequate screening tool.

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We applied a cobalt-porphyrin modified DNA as electrochemical marker, which was attached to nanoparticles, to detect specific DNA sequences. We compare the performance of gold and silver NPs in oligonucleotide sensors to determine if a change in metal will lead to either higher sensitivity or different selectivity, based on the redox behaviour of silver vs. gold.

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This study describes three closely related proteins, cloned from strains, that are lethal upon feeding to LeConte, the western corn rootworm (WCR). Mpp75Aa1, Mpp75Aa2 and Mpp75Aa3 were toxic to WCR larvae when fed purified protein. Transgenic plants expressing each mMpp75Aa protein were protected from feeding damage and showed significant reduction in adult emergence from infested plants by both susceptible and Cry3Bb1 and Cry34Ab1/Cry35Ab1-resistant WCR.

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