[Lipoid nephrosis of toxic origin. 2 cases].

Classically, the histological lesion observed in a drug-or heavy metal-induced nephrotic syndrome is membranous glomerulonephritis. We report two cases of "toxic" nephrotic syndrome with unusual histological features. One was secondary to mercury intoxication and the other, to D-penicillamine in a patient with rheumatoid arthritis.

[Essential thrombocythemia and hypertension as a result of stenosis of the renal artery].

Primary thrombocythemia may cause vascular thrombosis; it has been rarely involved in coronary atherosclerosis with myocardial infarction. We report three cases of renal arteries atherosclerosis occurring in association with primary thrombocythemia. These cases are three young women (20, 40 and 42 years old) with severe hypertension secondary to atherosclerosis with stenosis of renal arteries, one or both sided, and in association in one case with diffuse arterial stenosis.

[Plasma and urinary antithrombin III in the nephrotic syndrome in adults].

The occurrence of thromboembolism in nephrotic syndrome has been recently correlated with acquired antithrombin III (AT III) deficiency (and this raised the question of the prevention and treatment of thromboembolism with heparin). We studied AT III levels in plasma and urine in 39 adults with nephrotic syndrome. Three patients have had thromboembolic manifestations (before treatment with heparin).

[Congenital cardiopathies in adults. 179 cases].

Congenital heart disease in the adult represents less than 25 p. 100 of all congenital heart diseases; 179 out of 800 cases in the authors' experience. Atrial septal defect (ASD) is by far the most common (44 cases) especially in adults over 40 years of age.