Publications by authors named "C Gumbinger"

Background And Objectives: Covert brain infarcts (CBIs) in patients with first-ever ischemic stroke (IS) and atrial fibrillation (AF) are associated with an increased risk of stroke recurrence. We aimed to assess whether CBIs modify the treatment effect of early vs late initiation of direct oral anticoagulants (DOACs) in patients with IS and AF.

Methods: We conducted a post hoc analysis of the international, multicenter, randomized-controlled ELAN trial, which compared early (<48 hours after ischemic stroke for minor and moderate stroke, 6-7 days for major stroke) vs late (>48 hours for minor, 3-4 days for moderate, 12-14 days for major stroke) initiation of DOACs in patients with IS and AF.

View Article and Find Full Text PDF

Background And Aims: Previous observational data indicate that young adults treated with intravenous thrombolysis (IVT) for acute ischemic stroke have more favorable outcomes and less complications when compared to older adults. Given the limited data on this topic, we aimed to provide more evidence on clinical outcomes and safety in such patients, using a large international thrombolysis registry.

Methods: In this prospective multicenter study, we used data from the Thrombolysis in Ischemic Stroke Patients (TRISP) registry from 1998 to 2020.

View Article and Find Full Text PDF

With the increasing use of smartphone-based lifestyle interventions, it is important to understand whether people's preferred operating system (iOS or Android) is linked to their lifestyle habits. Our goal was to determine whether the choice of an iOS- or Android-powered smartphone independently affected daily health habits. We recruited participants for an online survey using the CloudResearch® Connect™ platform.

View Article and Find Full Text PDF
Article Synopsis
  • * Many low- and middle-income countries (LMICs) are beginning to establish telestroke services, indicating a potential shift in access to specialized stroke care.
  • * The analysis identified significant variations in network structures and technologies used, with 75% employing real-time video and image transfer, and a focus on quality monitoring in 74% of networks.
View Article and Find Full Text PDF

Background: Telemedicine provides specialized medical expertise in underserved areas where neurological expertise is frequently not available on a daily basis for hospitalized stroke patients. While tele-consultations are well established in acute stroke assessment, the value of telemedicine-based ward-rounds in the subsequent in-patient stroke management is unknown.

Methods: Four telemedicine stroke networks in Germany, implemented in eight out of 16 federal states, participate in this prospective observational multi-center study.

View Article and Find Full Text PDF