Publications by authors named "C Guinat"

In October 2019, South Korea's first case of African swine fever (ASF) was reported in wild boar in the north of the country. Despite the implementation of a 2300 km-long fencing strategy, the ASF wavefront continued to invade southward. Our study aimed to investigate the ASF wavefront dynamics in different regions of South Korea, as well as to assess the effectiveness of the fencing measures on ASF dispersal and wavefront velocity.

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Article Synopsis
  • The rise of clade 2.3.4.4b H5N1 avian influenza in 2021 has resulted in major poultry epidemics and increased infections in wild birds and mammals, necessitating new management strategies.
  • Poultry vaccination is becoming essential for controlling HPAI, as highlighted by France's vaccination program for domestic ducks, but broader changes are also needed to address logistical and trade issues.
  • To enhance regional biosecurity, it is important to focus on the spatial distribution of poultry farms and reduce farm concentration to prevent virus spread, which will ultimately reshape poultry production and trade practices.
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Selecting appropriate diagnostic methods that take account of the type of vaccine used is important when implementing a vaccination programme against highly pathogenic avian influenza (HPAI). If vaccination is effective, a decreased viral load is expected in the samples used for diagnosis, making molecular methods with high sensitivity the best choice. Although serological methods can be reasonably sensitive, they may produce results that are difficult to interpret.

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Avian influenza viruses (AIVs) of the H9N2 subtype have become widespread in Western Africa since their first detection in 2017 in Burkina Faso. However, the genetic characteristics and diffusion patterns of the H9N2 virus remain poorly understood in Western Africa, mainly due to limited surveillance activities. In addition, Mali, a country considered to play an important role in the epidemiology of AIVs in the region, lacks more comprehensive data on the genetic characteristics of these viruses, especially the H9N2 subtype.

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Several vaccines have been developed against highly pathogenic avian influenza (HPAI), mostly inactivated whole-virus vaccines for chickens. In the EU, one vaccine is authorised in chickens but is not fully efficacious to stop transmission, highlighting the need for vaccines tailored to diverse poultry species and production types. Off-label use of vaccines is possible, but effectiveness varies.

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