Prediction of the accumulation behavior of pesticides in PDMS-coated stir bars used as passive samplers in freshwaters.

Passive samplers accumulate organic contaminants at rates that depend on in-field exposure conditions such as freshwater flow velocity, water temperature and water quality. Time-weighted average concentrations can be determined by using a correction process such as the performance reference compound (PRC) method. This study presented a new approach to predict the accumulation behavior of pesticides in polydimethylsiloxane-coated stir bars under different exposure conditions and assign a specific PRC to each pesticide for quantitative purposes.

Feasibility and efficiency of delayed ovarian stimulation and metaphase II oocyte banking for fertility preservation and childbearing desire after fertility-impairing treatment.

The aim of our study was to evaluate the feasibility and efficiency of delayed ovarian stimulation and metaphase II oocyte banking for fertility preservation after fertility-impairing treatment regardless of the initial disease. We conducted a cohort study based on population of women < 40 years of age with diminished ovarian reserve caused by fertility-impairing treatment (n = 129). Three groups of women were compared according to the type of initial disease: hematological malignancies, solid tumors, and benign diseases.

[Fertility preservation and access to medically assisted reproduction for Trans people: Guidelines from French Professional Association for Transgender Health].

Many health care professionals are dealing with the issue of transgender people in their medical practice. In the field of reproduction, Trans people can benefit from fertility preservation before the introduction of hormonal treatment or surgery altering their fertility. This article, which is the result of a collaborative work of several reproductive professionals involved in the health of Trans people, provides an overview of the possibilities of fertility preservation and medically assisted reproduction techniques in France for Trans people.

Suspect screening of environmental contaminants by UHPLC-HRMS and transposable Quantitative Structure-Retention Relationship modelling.

A Quantitative Structure-Retention Relationship (QSRR) model is proposed and aims at increasing the confidence level associated to the identification of organic contaminants by Ultra-High Performance Liquid Chromatography hyphenated to High Resolution Mass Spectrometry (UHPLC-HRMS) in environmental samples under a suspect screening approach. The model was built from a selection of 8 easily accessible physicochemical descriptors, and was validated from a set of 274 organic compounds commonly found in environmental samples. The proposed predictive figure approach is based on the mobile phase composition at solute elution (expressed as % acetonitrile), that has the major advantage of making the model reusable by other laboratories, since the elution composition is independent of both the column geometry and the UHPLC-system.