Publications by authors named "C Gugliandolo"
Volcanic emissions in shallow vents influence the biogeochemistry of the sedimentary compartment, creating marked abiotic gradients. We assessed the spatial dynamics of the sediment compartment, as for the composition and origin of organic matter and associated prokaryotic community, in a volcanic shallow CO vent (Vulcano Island, Italy). Based on elemental (carbon, nitrogen content and their ratio) and isotopic composition (δC, δN and δS), the contribution of vent-derived organic matter (microbial mats) to sedimentary organic matter was high close to the vent, while the marine-derived end-members (seagrasses) contributed highly at increasing distance.
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- The mannose-rich exopolysaccharide EPS B3-15, derived from a thermophilic bacterium, shows potential as an antiviral and immunomodulatory agent, particularly in respiratory infections.
- In experiments with LPS-induced macrophages, EPS B3-15 significantly reduced inflammatory markers without harming cell viability and achieved a notable reduction in the adhesion of certain pathogenic bacteria.
- The study suggests that EPS B3-15 could be developed into a nasal spray and used as a surface-coating agent for medical devices due to its anti-inflammatory properties and effect on bacterial adhesion.
Background: Respiratory viral infections are a leading cause of severe diseases and mortality; therefore, novel treatments effective for their prevention are highly requested. Here, we identified a broad-spectrum antiviral activity of a natural exopolysaccharide, EPS T14, purified from a marine thermotolerant strain of strain T14.
Methods: The effects on human normal nasal epithelial cells (HNEpCs) following treatment with EPS T14 was evaluated at different time points and with increasing concentration of compound.
The bioconversion of agri-food waste into high-value products is gaining growing interest worldwide. Orange peel waste (OPW) is the main by-product of orange juice production and contains high levels of moisture and carbohydrates. In this study, the orange waste extract (OWE) obtained through acid hydrolysis of OPW was used as a substrate in the cultivation of the marine microalgae .
View Article and Find Full Text PDFWe report the ability of the crude biosurfactant (BS B3-15), produced by the marine, thermotolerant B3-15, to hinder the adhesion and biofilm formation of ATCC 27853 and ATCC 29213 to polystyrene and human cells. First, we attempted to increase the BS yield, optimizing the culture conditions, and evaluated the surface-active properties of cell-free supernatants. Under phosphate deprivation (0.
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