Publications by authors named "C Grundy"
Introduction: Achieving the ambitious goals of the Immunisation Agenda 2030 (IA2030) requires a deeper understanding of factors influencing under-vaccination, including timely vaccination. This study investigates the demand- and supply-side determinants influencing the timely uptake of key childhood vaccines scheduled throughout the first year of life in The Gambia.
Methods: We used two nationally-representative datasets: the 2019-20 Gambian Demographic and Health Survey and the 2019 national immunisation facility mapping.
Article Synopsis
- The study explored the links between HIV, frailty, and health-related quality of life in adults aged 40 and older in Zimbabwe, using various assessments to define and measure frailty.
- Of the 1,034 participants, 21.6% were living with HIV, with most knowing their status and receiving antiretroviral therapy, yet HIV status itself was not directly linked to increased frailty.
- However, longer duration of living with HIV increased the odds of frailty, while longer use of ART reduced those odds, suggesting that early initiation of ART may help decrease future frailty risk.
Article Synopsis
- Pakistan has one of the highest rates of tuberculosis (TB) in the world, and a study was conducted to assess the prevalence of TB in adults and the risk of M. tuberculosis infection in children in Karachi, focusing on areas with and without prior active case-finding (ACF) activities.
- The research involved surveys between March 2018 and May 2019, with almost 35,000 adults and over 1,500 children participating, revealing a higher prevalence of TB in areas with no prior ACF (421 cases per 100,000) compared to areas with prior ACF (279 cases per 100,000).
- The findings indicated that ACF efforts in Korangi district likely reduced TB prevalence and transmission,
Background: Youth have poorer HIV-related outcomes when compared to other age-groups. We describe the protocol for a cluster randomised trial (CRT) to evaluate the effectiveness of community-based, integrated HIV and sexual and reproductive health services for youth on HIV outcomes.
Protocol: The CHIEDZA trial is being conducted in three provinces in Zimbabwe, each with eight geographically demarcated areas (clusters) (total 24 clusters) randomised 1:1 to standard of care (existing health services) or to the intervention.
Introduction: The COVID-19 pandemic caused widespread morbidity and mortality and resulted in the biggest setback in routine vaccinations in three decades. Data on the impact of the pandemic on immunisation in Africa are limited, in part, due to low-quality routine or administrative data. This study examined coverage and timeliness of routine childhood immunisation during the pandemic in The Gambia, a country with an immunisation system considered robust.
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