Presence of dengue virus RNA in urine and oral fluid of laboratory-confirmed dengue patients: Implications for wastewater surveillance.

Introduction: Dengue cases in the Americas in 2024 have reached record highs, especially in Brazil. However, surveillance remains suboptimal and new methods are needed to monitor Dengue Virus (DENV) spread. To assess whether wastewater-based epidemiology would be a useful tool, we investigated the presence of DENV RNA in dengue patients' urine and oral fluid from an endemic area to inform how shedding in these fluids occurs and provide insight for wastewater surveillance.

Endothelin A receptor inhibition increases nitric oxide-dependent vasodilation independent of superoxide in non-Hispanic Black young adults.

Young non-Hispanic Black adults have reduced microvascular endothelial function compared with non-Hispanic White counterparts, but the mechanisms are not fully elucidated. The purpose of this study was to investigate the effect of endothelin-1 A receptor (ETR) and superoxide on cutaneous microvascular function in young non-Hispanic Black ( = 10) and White ( = 10) adults. Participants were instrumented with four intradermal microdialysis fibers: ) lactated Ringer's (control), ) 500 nM BQ-123 (ETR antagonist), ) 10 μM tempol (superoxide dismutase mimetic), and ) BQ-123 + tempol.

Comparison of Long-term Outcomes of Heparin Bonded Polytetrafluoroethylene and Autologous Vein Below Knee Femoropopliteal Bypasses in Patients with Critical Limb Ischaemia.

Objective/background: Endovascular first is the preferred therapy approach to critical limb ischaemia (CLI). However, in spite of new endovascular techniques, bypass surgery still plays an important role, especially in patients with complex anatomy in whom endovascular therapy is not considered feasible, or has failed. The goal of this study was to analyse the outcomes of prosthetic or autologous vein for femoropopliteal (P3) bypasses performed under the abovementioned conditions.

The Motor Unit Number Index (MUNIX) in sarcopenic patients.

Introduction: The cause of sarcopenia is still not fully understood. A multifactorial aetiology is discussed. Neurodegenerative aspects in the genesis of sarcopenia, such as loss of motoneurons, have not yet been explored to a sufficient extent.

Langmuir supercells: a mechanism for sediment resuspension and transport in shallow seas.

Recent measurements at a cabled sea-floor node in 15 meters of water off the coast of New Jersey suggest that Langmuir supercells, Langmuir circulations that achieve vertical scales equal to the water depth under extended storms, are an important mechanism for major sediment resuspension events on the extensive shallow shelves off the eastern U.S. coast.