Publications by authors named "C Gramond"
Introduction: Questions concerning under-reporting of occupational diseases (OD) linked to asbestos exposure are regularly voiced in France. Monitoring of the French multicenter Asbestos-Related Disease Cohort (ARDCO), which ensures post-occupational medical surveillance of subjects having been exposed to asbestos, provides information on (1) the medico-legal steps taken following screening by computed tomography (CT) for benign thoracic diseases, and (2) recognition of OD as a causal factor in malignant diseases.
Methods: OD recognition - and possible compensation - was analyzed in July 2021 among 13,289 volunteers in the cohort recruited between 2003 and 2005.
Article Synopsis
- This study aimed to explore how different aspects of asbestos exposure relate to pleural plaques (PP) in retired workers in France.
- A large screening program conducted from 2003 to 2016 involved 5,392 participants, with HRCT scans and detailed evaluations of their work history to gauge their asbestos exposure levels.
- The findings revealed complex, non-linear relationships where the risk of PP increased with higher cumulative asbestos exposure and longer periods since first exposure, while the odds decreased with longer times since last exposure.
Article Synopsis
- The study investigates how mothers' exposure to carbonaceous nanoscale particles (UNPs) while pregnant affects their children’s language development and behavior at age two.
- Researchers used data from a large French study, evaluating occupational exposure and assessing children’s language skills and autism risk using specialized tools.
- Results indicate that exposure to these particles is linked to delayed language development in children, but not to an increased risk of behavioral disorders like autism.
Article Synopsis
- Previous studies on the link between refractory ceramic fibers (RCFs), mineral wool fibers (MWFs), and pleural plaques have been inconsistent, often relying on chest radiographs, which are not very accurate.
- This research investigates whether cumulative exposure to RCFs, MWFs, and silica increases the risk of pleural plaques, and how this risk interacts with co-exposure to asbestos.
- Among 5,457 subjects screened with CT scans, the study found significant dose-response relationships, with higher cumulative exposure to RCFs and MWFs leading to an increased risk of pleural plaques, especially in individuals also exposed to asbestos.
Background: Occupational asbestos exposure is associated with pleural plaques (PP), a benign disease often seen as a marker of past exposure to asbestos and lung cancer. The association between these two diseases has not been formally proved, the aim of this study was to evaluate this association in the asbestos-related disease cohort (ARDCO) cohort.
Methods: ARDCO is a French multicentric cohort including workers formerly occupationally exposed to asbestos from 2003 to 2005.