Publications by authors named "C Gomercic"

Background: Achieving competence in endoscopic retrograde cholangiopancreatography (ERCP) requires extensive training. Recognizing the potential of simulator-based education for safe and effective skill development, we aimed to assess whether initial training with the Boškoski-Costamagna ERCP Trainer (BCT) is beneficial compared with conventional training alone (i.e.

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Article Synopsis
  • Variants in the PRSS1 and PRSS2 genes are linked to chronic pancreatitis (CP), prompting research into whether a deletion variant affecting two trypsinogen pseudogenes (PRSS3P2 and TRY7) might influence CP risk.
  • A study analyzed this deletion in over 4,000 participants from different countries and found that it is associated with a protective effect against CP, especially in French, German, and Japanese populations.
  • The research suggests that the deletion enhances the function of remaining genes, leading to regulated PRSS2 expression, which could be crucial in understanding CP susceptibility.
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Objectives: Severe acute pancreatitis (AP) is characterized by early microcirculation defects causing hypercoagulability. The purpose of this study was to evaluate the early predictive value of D-dimers in complicated AP.

Methods: This was a prospective single-center study conducted between September 2010 and April 2012.

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Article Synopsis
  • The study investigated endoscopic submucosal tunnel dissection (ESTD) as an alternative to endoscopic submucosal dissection (ESD) for removing gastroesophageal lesions in pigs.
  • Both techniques were found to have an 88.9% technical success rate, with ESTD achieving a 100% en bloc resection rate, but complications and costs were similar for both methods.
  • ESTD provided better quality histological specimens, suggesting it's a safe option but not necessarily superior to ESD for treatment effectiveness.
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Introduction: The management of post-operative anastomotic leakage and fistulas of the upper GI tract remains challenging. Fully covered stents are used despite a high risk of migration because of a better removability. The goal of our study was to evaluate the effectiveness of this new type of endoscopic stent in this indication.

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