Publications by authors named "C Geppert"
The critical relevance and importance of considering religion and spirituality (R/S) in academic and public discourse on bioethical issues and in the illness experiences of patients and families is difficult to deny. Yet, little is known about the nature and scope of R/S education in graduate bioethics training. We therefore conducted a literature review and survey of bioethics programs in the USA and a content analysis of relevant syllabi of courses.
View Article and Find Full Text PDFObjectives: Little is known on the mechanisms necessary to maintain the physiological adult human skin integrity. This study aims to quantitatively describe anatomical changes in systemic sclerosis (SSc)-skin compared to controls and investigate the underlying mechanisms.
Methods: Skin morphology was histologically assessed in twenty-three SSc-patients, eighteen controls and fifteen patients with hypertrophic scars.
A vast multitude of tasks in histopathology could potentially benefit from the support of artificial intelligence (AI). Many examples have been shown in the literature and first commercial products with FDA or CE-IVDR clearance are available. However, two key challenges remain: (1) a scarcity of thoroughly annotated images, respectively the laboriousness of this task, and (2) the creation of robust models that can cope with the data heterogeneity in the field (domain generalization).
View Article and Find Full Text PDFSecretomes of cancer-associated fibroblasts (CAFs) in colorectal cancer (CRC) contribute to malignancy. Detailed knowledge is available on the components and functions of CAF secretomes. Little is known about the regulation of CAF secretomes.
View Article and Find Full Text PDFArticle Synopsis
- The study focuses on the diagnostic challenges of colposcopy in women aged 50 and older, particularly those with postmenopausal status and transformation zone type 3 (TZ3), highlighting the role of endocervical curettage (ECC) in diagnosing cervical lesions.
- By analyzing data from colposcopies performed at Erlangen University Hospital between 2016 and 2023, researchers correlated Pap and HPV results with histologic findings from ECC.
- The findings reveal that ECC can effectively detect significant lesions, including high-grade cervical intraepithelial neoplasia (CIN) and invasive carcinoma, even in patients with normal colposcopic results, underscoring its importance in diagnostic procedures.