Publications by authors named "C Gazzaruso"

Purpose: The aim of this study is to prospectively evaluate whether individual and group Therapeutic Patient Education (TPE) can reduce the need to intensify treatment of diabetes and hypertension in newly diagnosed type 2 diabetic patients.

Methods: A total of 937 patients were recruited and followed-up for 42.7 ± 21.

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  • The study explores how dietary patterns, specifically adherence to a Mediterranean diet, relate to muscle health and the risk of sarcopenia in adults over 50 in southern Italy.
  • Researchers analyzed data from 528 participants, measuring muscle strength with handgrip tests and estimating muscle mass through bioelectrical impedance, using a food frequency questionnaire to identify dietary habits.
  • Results revealed that stronger adherence to the Mediterranean diet was linked to better muscle strength and a lower risk of sarcopenia, with significant differences noted in handgrip strength between the highest and lowest adherent groups.
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Objective: Polyphenol intake may prevent hepatic steatosis and cardiovascular disease by potentially improving endothelial function. The purposes of this study are to investigate the association between fatty liver disease and endothelial dysfunction and to test the effects of a nutraceutical containing extracts made from Citrus bergamia and Cynara cardunculus on peripheral vascular endothelial function in adults with liver steatosis.

Methods: We analyzed data from 32 individuals with hepatic steatosis and endothelial dysfunction (reactive hyperemia index ≤ 1.

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  • The study investigates long-COVID, a complex condition with no effective treatments, particularly focusing on cardiovascular symptoms like high heart rate and palpitations linked to mast cell activation (MCA).
  • Researchers administered histamine receptor blockers (fexofenadine and famotidine) to 14 patients with long-COVID symptoms over 20 days and compared results with 13 control subjects.
  • Results showed that 29% of treated patients experienced complete symptom resolution, with significant improvements in all treated individuals, supporting the idea that targeting histamine receptors may be a viable treatment for long-COVID.
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