Service delivery of at-home STI testing using self-collected samples: a qualitative investigation of values and preferences among adults in Rakai, Uganda.

Background Studies have shown that clients accept the self-collection of samples for sexually transmitted infection testing (SCS/STI testing), and at-home service delivery is a promising approach to expand diagnosis. However, few studies have examined client values surrounding service delivery in low-resource settings. This formative research study explores clients' service delivery values and preferences for at-home SCS/STI testing in rural Uganda.

Cost-effectiveness Analysis of the Technology-Enhanced Community Health Nursing Program for Adolescent Girls and Young Adult Women with Pelvic Inflammatory Disease.

Background: Pelvic inflammatory Disease (PID) disproportionately impacts adolescents and young adult women. The Technology-Enhanced Community Health Nursing (TECH-N) trial demonstrated the potential benefit of a novel community health intervention for adolescents with PID. We assess the cost-effectiveness of TECH-N compared to standard care.

L-Serovar Rectal Chlamydia trachomatis in Patients Who Were Male-Assigned at Birth Attending Two Sexual Health Clinics, Baltimore, Maryland 2009-2016.

Introduction: Lymphogranuloma venereum (LGV) caused by L-serovars of Chlamydia trachomatis (CT) is a sexually transmitted infection (STI) causing asymptomatic infection, and anogenital disease. Epidemiologically, LGV has been strongly associated with human immunodeficiency virus (HIV) infection.

Methods: Using a retrospective longitudinal study design, we first described unadjusted and adjusted associations between demographic and sociobehavioral characteristics and rectal (r) CT (rCT) and rLGV in sexual health clinic attendees in Baltimore, MD, between 2009 and 2016 at baseline visits.

Local emergence and global evolution of with high-level resistance to azithromycin.

Antimicrobial resistance in (Ng) has severely reduced treatment options, including azithromycin (AZM), which had previously been recommended as dual therapy with ceftriaxone. This study characterizes the emergence of high-level resistance to AZM (HLR-AZM) Ng in Baltimore, Maryland, USA, and describes the global evolution of HLR-AZM Ng. Whole genome sequencing (WGS) of 30 Ng isolates with and without HLR-AZM from Baltimore was used to identify clonality and resistance determinants.