Publications by authors named "C Garibaldi"
Postoperative radiotherapy (RT) has been shown to effectively reduce disease recurrence and mortality in breast cancer (BC) treatment. A critical step in the planning workflow is the accurate delineation of clinical target volumes (CTV) and organs-at-risk (OAR). This literature review evaluates recent advancements in deep-learning (DL) and atlas-based auto-contouring techniques for CTVs and OARs in BC planning-CT images for RT.
View Article and Find Full Text PDFArticle Synopsis
- The study addresses the advancement of synthetic CT (sCT) in MR-guided radiotherapy and aims to define current practices through a survey distributed among ESTRO members in 2023.
- Results showed that sCT is primarily used for pelvic treatments and conventional fractionation, with varying application across different areas and limited engagement in proton therapy.
- A strong consensus emerged for the need for standardized, vendor-neutral guidelines to improve the development and use of sCT in clinical settings, as many centers lack dedicated quality assurance programs.
Treatments at ultra-high dose rate (UHDR) have the potential to improve the therapeutic index of radiation therapy (RT) by sparing normal tissues compared to conventional dose rate irradiations. Insufficient and inconsistent reporting in physics and dosimetry of preclinical and translational studies may have contributed to a reproducibility crisis of radiobiological data in the field. Consequently, the development of a common terminology, as well as common recording, reporting, dosimetry, and metrology standards is required.
View Article and Find Full Text PDFPurpose: Radiomics is an emerging field that utilizes quantitative features extracted from medical images to predict clinically meaningful outcomes. Validating findings is crucial to assess radiomics applicability. We aimed to validate previously published magnetic resonance imaging (MRI) radiomics models to predict oncological outcomes in oral tongue squamous cell carcinoma (OTSCC).
View Article and Find Full Text PDFArticle Synopsis
- Scientists created a special nanoplatform made of cellulose that helps treat a type of breast cancer called triple negative breast cancer (TNBC).
- This platform uses sugar to target the cancer cells and deliver tiny particles called gold nanoparticles (AuNPs) right where they are needed.
- When X-rays are used with this new method, it can improve how well the treatment works, allowing doctors to use less radiation for the same effect.