Publications by authors named "C Garde"

Importance: Despite the benefits of goals-of-care (GOC) communication, many hospitalized individuals never communicate their goals or preferences to clinicians.

Objective: To assess whether a GOC video intervention delivered by palliative care educators (PCEs) increased the rate of GOC documentation.

Design, Setting, And Participants: This pragmatic, stepped-wedge cluster randomized clinical trial included patients aged 65 years or older admitted to 1 of 14 units at 2 urban hospitals in New York and Boston from July 1, 2021, to October 31, 2022.

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Chronic exposure to persistent organic pollutants (POPs) is suspected to contribute to the onset of breast cancer, but the impact on the evolution of patients after diagnosis is unclear. We aimed to analyze the contribution of long-term exposure to five POPs to overall mortality, cancer recurrence, metastasis, and development of second primary tumors over a global follow-up of 10 years after surgery in breast cancer patients in a cohort study. Between 2012 and 2014, a total of 112 newly diagnosed breast cancer patients were recruited from a public hospital in Granada, Southern Spain.

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Article Synopsis
  • Recent advancements in neuromuscular disease treatments could significantly improve patient outcomes, highlighting the importance of effective tools to measure motor function, like the Motor Function Measure (MFM).
  • The study aims to evaluate the quality of evidence surrounding MFM's measurement properties, specifically the 20-item version for young children and the original 32-item version, through a systematic review of existing validation and responsiveness research.
  • Analysis of 49 studies shows that MFM demonstrates strong reliability and validity across various neuromuscular diseases, with a particular emphasis on Spinal Muscular Atrophy (SMA), although further research is needed for specific diseases and measurement properties.
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  • The study aimed to evaluate the Kinect's effectiveness in capturing the movement and posture of individuals with spinal muscular atrophy (SMA) while they performed tasks from the Motor Function Measure rating scale.
  • A multicenter feasibility study involved scoring participants' performances both by in-person therapists (Score-T) and through digital data visualization with Kinect (Score-D), to compare their agreements and disagreements.
  • Results showed only 31.7% agreement for SMA type 2 participants and 76.2% for type 3, suggesting that while Kinect can't reliably automate scoring, it may help identify compensatory movements in patients.
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Article Synopsis
  • - Clinical image data analysis is evolving, requiring integration of imaging data into Clinical Data Warehouses (CDWs) while addressing challenges in interoperability and semantics, which led to the development of a web service called I4DW for querying pixel data.
  • - The implementation of I4DW was evaluated using a prostate cancer cohort, demonstrating efficient DICOM data transfer with average retrieval times of around 5.94 seconds for series and 0.9 seconds for metadata, achieving high precision (0.95) and complete recall (1).
  • - Future improvements for I4DW will focus on enhancing performance and ensuring patient data de-identification, while its design ensures scalability and can be applied across different clinical domains.
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