Histopathological data on six cases of hypothyroidism accompanying muscular chronic disease.

This study was carried out on 6 patients with myxedema that showed major muscular alterations. Light and electron microscopic examinations of the striated muscle structure revealed myxedematous myopathy lesions. Considering the existence of several hypotheses regarding the pathogeny of muscular alterations, the authors discuss the likelihood of a myogenic syndrome induced by an immunity deficit in hypothyroidism.