Robust and persistent B-cell responses following SARS-CoV-2 vaccine determine protection from SARS-CoV-2 infection.

Introduction: A clear immune correlate of protection from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has not been defined. We explored antibody, B-cell, and T-cell responses to the third-dose vaccine and relationship to incident SARS-CoV-2 infection.

Methods: Adults in a prospective cohort provided blood samples at day 0, day 14, and 10 months after the third-dose SARS-CoV-2 vaccine.

Responses of dairy cows to weekly individualized feeding strategies regarding their metabolic status.

In dairy farms, cows are commonly fed a mixture of forages and concentrates ad libitum. To improve the energy status and productivity of dairy cows, individualized feeding strategies have been proposed. One of these strategies is to provide supplemental concentrates to adjust the forage-to-concentrate ratio based on factors like individual milk yield or calculated energy balance.

Early inflammatory profiles predict maximal disease severity in COVID-19: An unsupervised cluster analysis.

Background: The inflammatory changes that underlie the heterogeneous presentations of COVID-19 remain incompletely understood. In this study we aimed to identify inflammatory profiles that precede the development of severe COVID-19, that could serve as targets for optimised delivery of immunomodulatory therapies and provide insights for the development of new therapies.

Methods: We included individuals sampled <10 days from COVID-19 symptom onset, recruited from both inpatient and outpatient settings.

Are drain essentials in kidney transplantation? Analysis of risk factors affecting the postoperative drainage.

Objective: The routine drain placement following renal transplantation is currently under debate. Its benefit is uncertain and may cause complications, particularly infectious ones. Some renal transplant patients have low-productive drains, that might be unnecessary.

On farm precision feeding of gestating sows based on energy and amino acids on farrowing performances and feeding behavior over 3 consecutive gestations.

Gestating sows are often fed a single diet throughout their gestation cycle, leading to situations of nutrients deficiency or excess at the individual level. The purpose of this study was to characterize, over 3 consecutive cycles, the impact of a precision feeding (PF), i.e.