[Impact of tumor lysis syndrome on the prognosis of pediatric mature B-cell lymphoma].

This study aimed to investigate the effect of tumor lysis syndrome (TLS) on the prognosis of children and adolescents with intermediate- or high-risk high-grade mature B-cell nonHodgkin lymphoma (HG B-NHL) . This study collected the clinical data and prognosis of 283 patients aged <18 years with newly diagnosed intermediate- or high-risk HG B-NHL treated at the Sun Yat-sen University Cancer Center from January 2010 to December 2022. The clinical characteristics, laboratory indicators during TLS, and prognosis of the patients were analyzed.

Autophagy mediated by ROS-AKT-FoxO pathway is required for intestinal regeneration in echinoderms.

Autophagy is essential for maintaining material balance and energy circulation and plays a critical role as a regulatory mechanism in tissue regeneration. However, current studies primarily describe this phenotype, with limited exploration of its molecular mechanisms. In this study, we provided the first evidence that autophagy is required for intestinal regeneration in Apostichopus japonicus and identified a previously unrecognized regulatory mechanism involved in this process.

The bioavailability and component characteristics of the aging dissolved organic matter (DOM) from the macroalgae Ulva prolifera in seawater.

The world's largest green tide, caused by Ulva prolifera, in the Yellow Sea negatively affects the social and economic development of China's coastal region. The dissolved organic matter (DOM) released from U. prolifera is a potential threat to the offshore ecological health.

Case Report: Type Ib Abernethy malformation.

Congenital extrahepatic portosystemic shunt, also known as Abernethy malformation, is a rare anatomic vascular malformation. Patients with Abernethy malformation may present with abdominal pain, abnormal liver function tests, hepatopulmonary syndrome, pulmonary hypertension, and/or portosystemic encephalopathy. Accurate identification of the shunt and portal vein and effective management of complications is vital in these patients.