Peer rejection and internet gaming disorder: the mediating role of relative deprivation and the moderating role of grit.

Background: Internet Gaming Disorder (IGD) is a new behavioral addiction. A large number of empirical studies have shown that Internet Gaming Disorder has a high level of comorbidity with other diseases, including depression, anxiety, obesity, internalizing and externalizing behavioral problems, however, little is known about the mediating and moderating mechanisms underlying this relation. The current study adopted a three-time longitudinal study investing the mediating effect of relative deprivation on the association between peer rejection and IGD, and whether this mediating effect was moderated by the grit.

TCDD inhibits the proliferation of C17.2 cells through the activation of the c-Cbl/β-catenin signaling pathway.

2,3,7,8-tetrachlordibenzo-p-dioxin (TCDD) belongs to the category of persistent environmental pollutants, and gestational exposure to TCDD can lead to cognitive, memory, and motor deficits, as well as altered neuron development in rodents. However, the molecular mechanisms underlying TCDD's neurotoxicity remine unclear. Neural stem cells (NSCs) possess the capacity for self-renewal and can generate various cell types within the brain, playing fundamental roles in brain development and regeneration.

Simultaneous Unbinned Differential Cross-Section Measurement of Twenty-Four Z+jets Kinematic Observables with the ATLAS Detector.

Z boson events at the Large Hadron Collider can be selected with high purity and are sensitive to a diverse range of QCD phenomena. As a result, these events are often used to probe the nature of the strong force, improve Monte Carlo event generators, and search for deviations from standard model predictions. All previous measurements of Z boson production characterize the event properties using a small number of observables and present the results as differential cross sections in predetermined bins.

Numerical simulation and experimental validation of light modulation by laser-ablated ripples on fused silica surfaces.

Laser ablation is a commonly employed technique to enhance the damage resistance of fused silica optics due to its non-contact nature and the absence of polishing aids. However, during the ablation process, laser-induced ripples are inevitably formed, posing significant risks by potentially lowering the laser-induced damage threshold (LIDT). This study investigates the impact of these laser-ablated ripples on damage resistance using numerical models that account for electromagnetic fields, heat transfer, and solid mechanics.

Gastric cancer genomics study using reference human pangenomes.

A pangenome is the sum of the genetic information of all individuals in a species or a population. Genomics research has been gradually shifted to a paradigm using a pangenome as the reference. However, in disease genomics study, pangenome-based analysis is still in its infancy.