Publications by authors named "C G Toby Mathias"
Article Synopsis
- The study investigates how social and home environments influence early substance use initiation (SUI) in adolescents, particularly focusing on alcohol (AUI) and cannabis (CUI) use.
- It examines whether family history of substance use disorders (FH+) affects the relationship between these environmental factors and SUI.
- Findings reveal that risky peer affiliations increase the risk of AUI and CUI regardless of FH status, but a strong mother-youth relationship can provide protection from CUI, which is weakened for those with a FH+.
Article Synopsis
- The study explores challenges in lung cancer biomarker testing due to tissue inadequacy and operational issues, implementing a tailored molecular testing approach in Brazil.
- From 1,272 lung cancer samples analyzed, a significant percentage were ineligible for testing due to insufficient tissue quality or quantity, with specific mutations and alterations being most commonly observed.
- Results suggest that while non-NGS tests provided some diagnostic information, a substantial portion of patients could only access reduced molecular testing coverage, impacting the detection of actionable cancer drivers.
Advancements in LAMP-Based Diagnostics: Emerging Techniques and Applications in Viral Detection with a Focus on Herpesviruses in Transplant Patient Management.
Ana Cláudia Martins Braga Gomes Torres Carolina Mathias Suelen Cristina Soares Baal Ana Flávia Kohler Mylena Lemes Cunha
Int J Mol Sci
October 2024
Article Synopsis
- - LAMP (Loop-mediated isothermal amplification) is a fast and effective method for diagnosing diseases, especially useful in point-of-care settings, and has evolved with adaptations for multiplex detection, allowing for testing multiple targets simultaneously.
- - The technique gained popularity during the COVID-19 pandemic for diagnosing various viruses, but there is limited research on its effectiveness in detecting Herpesviridae, which are significant for immunocompromised patients.
- - This review discusses recent advancements in LAMP technology, current research trends, and the challenges related to detecting Herpesviridae, stressing its importance for patient care.
Background: Prolonged grief is a chronic and debilitating condition that affects millions of persons worldwide. The aim of this study was to use a qualitative approach to better understand how relatives with prolonged grief disorder perceive what does or not help them and whether they were able to make recommendations.
Methods: Participants were all relatives of deceased patients admitted to 26 palliative care units involved in the FamiLife study; relatives were included if diagnosed with prolonged grief symptoms (i.