Red lesion in fundus image with hexagonal pattern feature and two-level segmentation.

Red lesion identification at its early stage is very essential for the treatment of diabetic retinopathy to prevent loss of vision. This work proposes a red lesion detection algorithm that uses Hexagonal pattern-based features with two-level segmentation that can detect hemorrhage and microaneurysms in the fundus image. The proposed scheme initially pre-processes the fundus image followed by a two-level segmentation.

Current Perspectives and Future Prospects of mRNA Vaccines against Viral Diseases: A Brief Review.

The mRNA vaccines replace our conventional vaccines (live-attenuated and inactivated vaccines) due to their high safety, efficacy, potency and low cost for their manufacturing. Since these many years, the use of these mRNA vaccines has been restricted as they are unstable and their low efficiency in delivery. But now, these problems have been solved by recent technological advances.

Autoimmune Hemolytic Anaemias in Pregnancy: Experience in a Tertiary Care Hospital in South India.

Background: Autoimmune hemolytic anaemia is very rare and there is limited data regarding their pregnancy outcomes. Hence we aimed to study the maternal and perinatal outcomes in pregnancies with autoimmune hemolytic anaemias (AIHA).

Methods: A retrospective descriptive study of pregnant women with AIHA, who delivered at SJMCH between January 2011 and January 2016 was carried out.

Bio-inspired nickel nanoparticles of pyrimidine-Schiff base: anticancer, BSA and DNA interactions, molecular docking and antioxidant studies.

In this work, interactions of pyrimidine derivative Schiff base ligand (DMPMM) were studied and its stabilized powder nickel nanoparticles (DMPMM-NiNPs) were synthesized and various biological studies were evaluated. DNA binding studies of CT-DNA with prepared compounds in Tris-HCl/NaCl buffer were carried out by traditional UV-Visible and fluorescence spectroscopic methods, viscosity measurements and cyclic voltammetry. Results showed that the small scale of DMPMM had less activity to interact with biological systems and when it assembled on nickel nanoparticles surface the activity increased.