Publications by authors named "C G S Sarma"

Context.—: Salivary gland (SG) neoplasms (SGNs) display considerable immunophenotypic diversity. A significant proportion of SG carcinomas develop metastases with increased diagnostic difficulty at metastatic sites.

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Background: Fine-needle aspiration cytology (FNAC) is the first-line diagnostic procedure for salivary gland masses. Secretory carcinoma (SC) is characterized by ETV6 and RET rearrangements detected by fluorescence in situ hybridization (FISH) or reverse transcriptase-polymerase chain reaction optimized for paraffin-embedded and fresh-frozen tissue, respectively. The authors performed FISH on cytological material to assess its role in the diagnosis of SC.

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Article Synopsis
  • Distant metastasis from salivary gland secretory carcinoma (SC) is uncommon, typically spreading to the lungs and pleura, with unique cytomorphological features observed in serous effusions of affected patients.
  • Two cases of ETV6::NTRK3 fusion-positive SC showed tumor cells in pleural fluid that resembled adenocarcinomas, complicating diagnosis since they could be mistaken for lung cancer.
  • Immunohistochemical analysis indicated pan-TRK positivity, suggesting that testing for NTRK3 fusion is essential not only for diagnosis but also for guiding targeted therapy with selective TRK inhibitors.
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Background And Aims: Accurate blood pressure measurements are the mainstay for the efficient management of abrupt cardiovascular changes during reperfusion in liver transplant. We sought to compare the femoral and radial pressures during reperfusion and at baseline, 1 h in dissection: portosystemic shunt, reperfusion, at bile duct anastomosis.

Methods: A retrospective study was performed amongst 102 adult patients who underwent R lobe living donor liver transplantation.

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Diabetes is a globally prevalent chronic metabolic disease characterized by blood glucose levels higher than the normal levels. Sugar, a common constituent of diet, is also a major factor often responsible for elevating the glucose level in diabetic patients. However, diabetic patients are more prone to eat sweets amongst the human population.

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