Development, validity, and reliability of the Street Food and Beverage Tool: (SFBT).

Objective: To develop and evaluate the validity and reliability of the Street Food and Beverage Tool (SFBT).

Design: This methodological study contains two phases: a) tool development, which involves conducting a systematic review followed by expert evaluation of the items, the creation of a Nutritional Healthfulness Index (NH), and pilot testing; and b) evaluation of the Tool's Validity and Reliability: Content validity was judged by an external technical group, which evaluated the adequacy and pertinence of each tool item. Construct validity was evaluated around schools by testing the hypothesis: In high-income areas, there will be greater availability of healthy food and beverages at street food outlets (SFOs), as measured by the NH-index.

First isolation of the Sindbis virus in mosquitoes from southwestern Spain reveals a new recent introduction from Africa.

Sindbis virus (SINV), is an of the family . This zoonotic arbovirus is transmitted by mosquitoes, primarily from the genus, with bird species acting as amplifying vertebrate hosts. Occasionally it can also affect humans that are accidental hosts.

Asymmetric Synthesis of 2-Arylethylamines: A Metal-Free Review of the New Millennium.

2-Arylethylamines are presented in several natural bioactive compounds, as well as in nitrogen-containing drugs. Their ability to surpass the blood-brain barrier makes this family of compounds of especial interest in medicinal chemistry. Asymmetric methodologies towards the synthesis of 2-arylethylamine motives are of great interest due to the challenges they may present.

Bemiparin in neonatal thrombosis: therapeutic dosing and safety.

Objective: To evaluate the therapeutic dose and safety of bemiparin in neonatal thrombosis treatment.

Study Design: A retrospective review was conducted on infants treated with bemiparin between 2018 and 2023 at a tertiary hospital.

Results: 72 neonates with a mean gestational age of 37 weeks were included.

EGFR-targeting polydopamine nanoparticles co-loaded with 5-fluorouracil, irinotecan, and leucovorin to potentially enhance metastatic colorectal cancer therapy.

Despite all prevention programs, many cases of colorectal cancer (CRC) are diagnosed when they have already metastasized. Herein, chemotherapy is required, and combination of 5-fluorouracil, irinotecan, and leucovorin (FOLFIRI) is one of the first-line treatments chosen. However, it is so toxic that compromises patient outcomes.