Renopancreatic Transplantation: Evaluation of 15 Years in 131 Patients.

Background: The most common multiple-organ transplant is the simultaneous pancreas-kidney transplantation (SPK). It is usually offered to patients who have insulin-dependent diabetes mellitus and those with diabetic nephropathy and renal failure that has already been established. In this study we present the results of 15 years of SPK in a transplant hospital center in Paraná, Brazil, and evaluated survival, immunosuppression, and transplant-related problems.

Reciprocal influences between ambulatorial peritoneal dialysis and pulmonary function.

The aim of this study was to verify if dialysis solution volumes used in patients on continuous ambulatory peritoneal dialysis (CAPD) interfere with pulmonary function and if the pulmonary volumes interfere with the lymphatic absorption of the peritoneal cavity. We submitted 10 CAPD patients with a mean age of 48 +/- 18 years and on CAPD for 35 +/- 27 months to the following evaluations: first, measurement of the lymphatic absorption from the peritoneal cavity; second, measurement of the hydrostatic intraperitoneal pressure; and third, expirometry with the peritoneal cavity full of dialysis solution and empty. There were no differences between the expirometry results obtained with the peritoneal cavity full and empty of dialysis solution, and the results were in accordance with the prediction for this population.

Potassium is not a good solute to estimate residual volume in CAPD.

Residual volume is defined as the volume of dialysate remaining in the peritoneal cavity after complete drainage of fluid. In this study the residual volume was estimated in 9 patients, age 42 +/- 9 years, on continuous ambulatory peritoneal dialysis (CAPD) for 14 +/- 12 months, using two different solutes: dextran 70 and potassium. The residual volume was calculated from the change induced in drain dialysate solute concentration by the known volume and solute concentration of the newly infused dialysis solution.