Publications by authors named "C G Humphries"

Background And Objectives: Heart disease and diabetes are leading causes of death in the U.S., with timely screening, referrals, and education being critical for effective treatment.

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Introduction: Acute liver failure (ALF) has no effective treatment other than liver transplantation and is commonly caused by paracetamol overdose. New treatments are needed to treat and prevent ALF. Alternatively-activated macrophages (AAMs) can promote resolution of liver necrosis and stimulate hepatocyte proliferation.

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Acute liver injury (ALI) has a clear requirement for novel therapies. One emerging option is the use of alternatively activated macrophages (AAMs); a distinct subtype of macrophage with a role in liver injury control and repair. In this comprehensive review, we provide an overview of the current limited options for ALI, and the potential advantages offered by AAMs.

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While the two types of intransitive verbs, i.e., unergative and unaccusative, are hypothesised to be syntactically represented, many have proposed a semantic account where abstract properties related to agentivity and telicity, often conceptualised as binary properties, determine the classification.

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Article Synopsis
  • The Royal College of Emergency Medicine's Toxicology Special Interest Group partnered with the UK National Poisons Information Service and Guy’s and St Thomas’ NHS Foundation Trust to create guidance for emergency department clinicians on handling acute opioid toxicity in adults.
  • The guidance includes advice on identifying cases of acute opioid toxicity and offers recommendations for treatment options and secondary prevention strategies.
  • Emphasis is placed on utilizing the best available evidence to inform these recommendations and improve patient care.
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