Publications by authors named "C Foulon"
Expression of concern for 'Heat-based transdermal delivery of a ramipril loaded cream for treating hypertension' by Anna Voronova , , 2022, , 12247-12256, https://doi.org/10.1039/D2NR02295H.
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- This study evaluates how effective deep-learning models, specifically a 3D U-Net network, are at quickly generating disconnectomes to predict neuropsychological outcomes in stroke patients one year post-stroke.
- The model was trained on 1333 synthetic lesions and then applied to 1333 actual stroke lesions, leading to the creation of deep-disconnectomes much faster than existing methods—approximately 720 times quicker.
- The findings show that these deep-disconnectomes have an impressive predictive accuracy of 85.2% for neuropsychological scores, marking a significant improvement over traditional disconnectome approaches and potentially enhancing stroke survivors' prognostic assessments.
Stroke remains a leading cause of mortality and long-term disability worldwide, with variable recovery trajectories posing substantial challenges in anticipating post-event care and rehabilitation planning. In response, we established the NeuralCup consortium to address these challenges by benchmarking predictive models of stroke outcome through a collaborative, data-driven approach. This study presents the findings of 15 participating teams worldwide who used a comprehensive dataset including clinical and imaging data, to identify and compare predictors of motor, cognitive, and emotional outcomes one-year post-stroke.
View Article and Find Full Text PDFThis research work dives into the complexity of hot-melt extrusion (HME) and its influence on drug stability, focusing on solid dispersions containing 30% of glibenclamide and three 50:50 polymer blends. The polymers used in the study are Ethocel Standard 10 Premium, Kollidon SR and Affinisol HPMC HME 4M. Glibenclamide solid dispersions are characterized using thermal analyses (thermogravimetric analysis (TGA) and differential scanning calorimetry), X-ray diffraction and scanning electron microscopy.
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