Publications by authors named "C Fontes"

This study investigates the use of recombinant peptidases (EC 3.4) to improve protein hydrolysis and digestibility in , with a focus on addressing the challenge of reduced protein bioavailability for monogastric animals due to resistant protein-pigment formations, such as phycocyanin, and increased digesta viscosity caused by jellification properties. A library of 192 peptidases was generated, from which 142 soluble peptidases were expressed in and subsequently screened for activity against an suspension .

View Article and Find Full Text PDF

Background:  Optic neuritis is an inflammation of the optic nerve caused by genetic factors, external influences, and the activation of cross-reactive immune responses to infections.

Objective:  To describe the clinical and epidemiological characteristics of patients presenting optic neuritis as the initial symptom of some demyelinating diseases, divided among multiple sclerosis (MS), neuromyelitis optica spectrum disorder (NMOSD), and myelin oligodendrocyte glycoprotein-immunoglobulin G (MOG-IgG)-associated disorders (MOGADs).

Methods:  Thirty-eight patients who had optic neuritis as their first symptom and later developed MS, NMOSD, or MOGADs were analyzed.

View Article and Find Full Text PDF

The self-consistent inclusion of plasma effects in opacity calculations is a significant modeling challenge. As density increases, such effects can no longer be treated perturbatively. Building on a a recently published model that addresses this challenge, we calculate opacities of oxygen at solar interior conditions.

View Article and Find Full Text PDF
Article Synopsis
  • The diversity of β-glucans leads to their various biological functions, necessitating multiple enzymes for their assembly and breakdown, along with new discoveries for potential biotechnological uses.
  • Recent studies have identified and characterized two bacterial β-glucanases, LaGH157 and BcGH157, from the glycoside hydrolase family 157, detailing their structures and functions in hydrolysis.
  • Both enzymes display optimal activity at specific pH and temperature ranges and exhibit unique cleavage patterns, expanding knowledge on β-glucan processing and suggesting future applications in biotechnology.
View Article and Find Full Text PDF
Article Synopsis
  • - The study examines the impact of platelet-rich plasma (PRP) on uterine inflammation and pregnancy rates in jennies (female donkeys) inseminated with frozen donkey semen, which generally shows lower success in jennies compared to mares.
  • - Three groups of jennies were tested: a control group with no treatment, a group receiving a single PRP infusion, and a group getting double PRP infusions around ovulation and artificial insemination (AI).
  • - Results indicated that while S-PRP reduced intrauterine fluid (IUF) accumulation shortly after AI, no significant differences were observed in pregnancy rates among groups, suggesting PRP treatments did not effectively improve outcomes for jennies
View Article and Find Full Text PDF