Low rates of aortic surveillance imaging and clinical follow-up in patients with acute aortic dissection.

Objectives: Patients that survive acute aortic dissection (AD) remain at high risk of morbidity/mortality from structural changes of the aorta. Aortic surveillance is challenging, especially within a tertiary referral center. Our aim was to identify follow-up imaging and appointment rates, and factors associated with incomplete surveillance in patients with acute AD.

Preliminary analyses of tryptophan, kynurenine, and the kynurenine: Tryptophan ratio in plasma, as potential biomarkers for systemic chlamydial infections in koalas.

Chlamydiosis is the major infectious disease responsible for significant morbidity and mortality in free-living koalas. Recently, it was reported that 28.5% of koalas infected with chlamydiosis were presented with no overt clinical signs.

Large language models can accurately populate Vascular Quality Initiative procedural databases using narrative operative reports.

Objectives: Participation in the Vascular Quality Initiative (VQI) provides important resources to surgeons, but the ability to do so is often limited by time and data entry personnel. Large language models (LLMs) such as ChatGPT (OpenAI) are examples of generative artificial intelligence (AI) products that may help bridge this gap. Trained on large volumes of data, the models are used for natural language processing (NLP) and text generation.

Cost-effectiveness of viral load testing for transitioning antiretroviral therapy-experienced children to dolutegravir in South Africa: a modelling analysis.

Background: For children with HIV on antiretroviral therapy (ART), transitioning to dolutegravir-containing regimens is recommended. The aim of this study was to assess whether introducing viral load testing to inform new nucleoside or nucleotide reverse transcriptase inhibitors (NRTIs) for children with HIV and viraemia alongside dolutegravir-based ART is beneficial and of good economic value.

Methods: We used the Cost-Effectiveness of Preventing AIDS Complications-Pediatric model to project clinical and cost implications of three strategies among a simulated cohort of South African children aged 8 years with HIV receiving abacavir-lamivudine-efavirenz: (1) continue current ART (no dolutegravir; abacavir-lamivudine-efavirenz); (2) transition all children with HIV to dolutegravir, keeping current NRTIs (dolutegravir; abacavir-lamivudine-dolutegravir); or (3) transition to dolutegravir based on viral load testing (viral load plus dolutegravir), keeping current NRTIs if virologically suppressed (abacavir-lamivudine-dolutegravir, 70% of cohort) or switching abacavir to zidovudine (zidovudine) if viraemic (zidovudine-lamivudine-dolutegravir, 30%).

A pilot prospective study of forward-looking infrared (FLIR) camera measurements to predict postoperative wound complications in high-energy lower extremity fractures.

Purpose: To prospectively determine if forward-looking infrared (FLIR) camera temperature measurements can predict postoperative wound complications in high-energy lower extremity fractures.

Methods: This is a prospective cohort study from a single level 1 trauma centre. Adult patients who sustained unilateral high-energy lower extremity fractures (tibial plateau, tibial plafond, trimalleolar ankle, midfoot, or calcaneus fractures) were included in the study.