Publications by authors named "C Fernandez-Pacheco"
Article Synopsis
- A study assessed the effects of maternal feed restriction (MFR) on the health and development of pregnant rabbit does by implementing different feeding schedules during gestation.
- Results showed that longer periods of feed restriction led to smaller fetuses, yet did not significantly impact the overall health and productivity of the does post-birth.
- While hormonal and metabolic changes occurred during pregnancy, particularly in the group with the longest restriction, overall metabolic condition and welfare remained unaffected after lactation.
Female reproductive mucosa must allow allogenic sperm survival whereas at the same time, avoid pathogen infection. To preserve sperm from neutrophil attack, neutrophils disappear from the vagina during the ovulatory phase (high estradiol); although the mechanisms that regulate neutrophil influx to the vagina during insemination remain controversial. We investigated the sex hormone regulation of the neutrophil migration through the cervix during insemination and revealed that ovulatory estradiol dose fades the CXCL1 epithelial expression in the ectocervix and fornix; hence, retarding neutrophil migration and retaining them in the epithelium.
View Article and Find Full Text PDFEstradiol-based therapies predispose women to vaginal infections. Moreover, it has long been known that neutrophils are absent from the vaginal lumen during the ovulatory phase (high estradiol). However, the mechanisms that regulate neutrophil influx to the vagina remain unknown.
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