Objectives: Ceftaroline, a broad-spectrum cephalosporin, has activity against Gram-positive and several Gram-negative bacteria (GNB). This study aimed to evaluate the antimicrobial activity of ceftaroline and comparators against isolates causing skin and soft tissue infections (SSTIs) and respiratory tract infections (RTIs) collected in Latin America (LATAM) in 2016-2020 as part of the Antimicrobial Testing Leadership and Surveillance program (ATLAS).
Methods: Minimum inhibitory concentrations were determined using both Clinical and Laboratory Standards Institute (CLSI) and European Committee on Antimicrobial Susceptibility Testing (EUCAST) criteria.
Objectives: Ceftazidime-avibactam (CAZ-AVI) combines ceftazidime and a reversible β-lactamase inhibitor that has shown activity against multidrug-resistant (MDR) Enterobacterales and P. aeruginosa. Using data from the Antimicrobial Testing Leadership and Surveillance program (ATLAS), this study examined the in vitro antimicrobial activity of CAZ-AVI and other antibiotics against Gram-negative bacteria collected from Chilean hospitals between 2015 and 2021.
View Article and Find Full Text PDFBackground: Ceftazidime-avibactam (C/A), has shown reduction in mortality rates and risk of nephrotoxicity, compared to colistin, conventional therapy.
Aim: To estimate the cost-effectiveness of C/A versus colistin + meropenem in the treatment of infections due to carbapenem-resistant Enterobacteriaceae (CRE) in Chile.
Methods: An economic decision tree type model was adapted.
Salmonellosis affects humans more frequently than any other foodborne disease, and it causes severe economic losses in the poultry industry. A cross-sectional study was carried out to estimate the prevalence of Salmonella spp. in laying hen farms in the Tolima region of Colombia.
View Article and Find Full Text PDFTuberculosis (TB) is a public health problem in Venezuelan indian communities. This study describes differences in hematological parameters in TB patients from two populations, Warao indians (WP) and creoles (CP). Control groups included Warao adults (WC) and children (WCh) as well as creole adults (CC).
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