Publications by authors named "C Faisant"
Idiopathic non-histaminergic acquired angioedema (InH-AAE) is a rare disease characterized by AE resistant to antihistamines and a chronic course. We report five new cases of InH-AAE (two women and three men) with a rapid and dramatic response to the anti-immunoglobulin-E antibody omalizumab. In our literature review, we found 13 other relevant cases with a good response to this treatment.
View Article and Find Full Text PDFHereditary angioedema (HAE) is a rare disease associated with either a quantitative or qualitative deficiency in C1-inhibitor (C1-INH) or normal C1-INH. HAE with normal C1-INH is associated in 20% of cases with mutations in the gene for factor XII (FXII) or FXII-HAE. A recent review described 41 families, including 14 German and 15 Spanish families.
View Article and Find Full Text PDFArticle Synopsis
- Idiopathic histaminergic acquired angioedema (IH-AAE) is a frequent cause of recurring angioedema without wheals, linked to mast cell activity and related to chronic urticaria (CU).
- A study identified 31 patients (15 men and 16 women) averaging 50 years old, who experienced an average diagnosis delay of 6.3 years, with 38.7% having a history of allergies.
- Attacks lasted about 28.1 hours, primarily affected the upper respiratory tract, and often required higher than recommended doses of anti-histamines for symptom control, indicating a benign yet challenging condition.
Introduction: Bradykinin-mediated angioedema (AE) is a rare side effect of some medications, including angiotensin converting enzyme inhibitors (ACEi) and angiotensin receptor blockers (ARB). In France, side-effects to treatments are reported to the national pharmacovigilance database.
Methods: The national MedDRA database was searched using the term "angioedema".