Publications by authors named "C F Lanata"
Background And Purpose: Bioavailability studies and observational evidence suggest that heme iron (HI) may have greater impact on iron status indicators compared with non-heme iron (NHI). This systematic review and meta-analysis aimed to review the current evidence on the effect of the administration of HI compared with NHI for improving iron status in non-hospitalized population groups.
Methods: We searched Pubmed, CENTRAL, Scopus, Web of Science, and LILACS from inception to July 2024.
Background: Systemic lupus erythematosus (SLE) has numerous symptoms across organs and an unpredictable flare-remittance pattern. This has made it challenging to understand drivers of long-term SLE outcomes. Our objective was to identify whether changes in DNA methylation over time, in an actively flaring SLE cohort, were associated with remission and whether these changes meaningfully subtype SLE patients.
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- - Norovirus accounts for 18% of acute gastroenteritis (AGE) cases globally, and this study focuses on its incidence in Lima, Peru, while exploring the potential effects of introducing a norovirus vaccine.
- - In a 6-month study involving 498 healthy children aged 5 to 18 months, researchers found that 32% of AGE cases were positive for norovirus, with a significant number of co-infections from bacteria like Campylobacter and Salmonella.
- - The findings indicate that norovirus is a major cause of AGE in this population, highlighting the need for an effective vaccine to improve public health outcomes, especially given the high coverage of the oral rotavirus vaccine among the children studied.
Article Synopsis
- Physical activity improves symptoms in people with systemic lupus erythematosus (SLE), but the underlying mechanisms were unclear until this study explored immune cell differences among active vs. inactive patients.
- A cohort of 123 SLE patients underwent analysis of immune cells and gene expression through advanced RNA sequencing, revealing that sedentary patients had greater CD4+ T cell lymphopenia and an overall proinflammatory gene expression profile.
- The study indicates that increased physical activity could reduce levels of proinflammatory cytokines and improve immune function in SLE patients, suggesting potential therapeutic benefits of regular exercise for this condition.
Objectives: To characterize factors associated with parental willingness for their children participation in a COVID-19 vaccine trial, use of different COVID-19 vaccines and acceptance of a third vaccine dose.
Methods: Parents of children aged 12-17 years in Lima, Perú were asked to complete an online questionnaire via social networks, from November 9, 2021, to April 23, 2022. We calculated crude and adjusted prevalence ratios with 95% confidence intervals to compare factors with the mentioned outcomes.