Clinical effectiveness of an online psychoeducational and psychotherapeutic programme for caregivers of children newly diagnosed as autistic: a parallel, assessor-masked, randomised controlled trial in the UK (REACH-ASD).

Background: Caregivers of autistic children experience particularly poor levels of mental health and increased caregiving complexities. Proactive post-diagnostic family support is recommended but is inconsistently implemented, largely not evidence based, and does not directly address caregiver mental health. This study aimed to test the clinical effectiveness of the Empower-Autism programme plus treatment as usual versus the usual local post-diagnostic psychoeducation offer plus treatment as usual on caregiver mental health at the 52-week follow-up.

Data retention in awake infant fMRI: Lessons from more than 750 scanning sessions.

Functional magnetic resonance imaging (fMRI) in awake infants has the potential to reveal how the early developing brain gives rise to cognition and behavior. However, awake infant fMRI poses significant methodological challenges that have hampered wider adoption. The present work takes stock after the collection of a substantial amount of awake infant fMRI data across multiple studies from two labs at different institutions.

Allostatic Load And Cardiovascular Disease: A Systematic Review.

Introduction: Cardiovascular disease (CVD) is a leading cause of morbidity and mortality. In the past three decades, allostatic load - a physiological representation of cumulative life stress - has been associated with increased risk of CVD incidence and mortality. Additionally, differences in allostatic load may partially explain persistent disparities in CVD outcomes.

Movies reveal the fine-grained organization of infant visual cortex.

Studying infant minds with movies is a promising way to increase engagement relative to traditional tasks. However, the spatial specificity and functional significance of movie-evoked activity in infants remains unclear. Here, we investigated what movies can reveal about the organization of the infant visual system.