Publications by authors named "C F Carson"
Antimicrobial resistance (AMR) has been described as a silent pandemic - one that is ever-present, ubiquitous and growing but often insidious and overlooked. A true One Health issue, AMR affects people, animals, plants, crops and the environment in complex and interconnected but poorly understood ways, and the impact will continue to increase. In animals, AMR affects animal health, welfare and production and is also considered a food safety, food security and substantial economic issue.
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- Researchers assessed circulating tumor DNA (ctDNA) as a biomarker for monitoring cancer treatment in patients with various renal cell carcinoma (RCC) types, finding it could improve clinical outcomes.
- The study involved 92 patients undergoing treatment, monitoring ctDNA changes and their association with progression-free survival (PFS), revealing that patients with serial ctDNA negativity had better PFS compared to those who remained ctDNA positive.
- Results indicate that regular ctDNA monitoring can provide valuable prognostic information during treatment or surveillance, showing strong correlation with patient outcomes.
Biobanks hold immense potential for genomic research, but fragmented data and incompatible tools slow progress. This workshop equipped participants with Nextflow, a powerful workflow language to streamline bioinformatic analyses across biobanks. We taught participants to write code in their preferred language and demonstrated how Nextflow handles the complexities, ensuring consistent, reproducible results across different platforms.
View Article and Find Full Text PDFObjective: To explore associations between maternal body mass index (BMI) in early pregnancy and childhood infections.
Design: Birth cohort study linked to primary care records.
Setting: Bradford, UK.