Publications by authors named "C Ezpeleta"
Effectiveness of influenza vaccination in preventing confirmed influenza cases and hospitalizations in Northern Spain, 2023/24 season: A population-based test-negative case-control study.
Int J Infect Dis
February 2025
Objective: We estimated the influenza vaccination effectiveness (IVE) in preventing medical consultations and hospitalizations due to influenza during the 2023/24 season.
Methods: Two test-negative case-control studies analyzed patients who consulted primary healthcare or were hospitalized for respiratory symptoms and were tested for influenza by PCR in the 2023/24 season in Navarre, Spain. Influenza vaccination status in the current and previous seasons was compared between confirmed influenza cases and test-negative controls.
Article Synopsis
- Bartonella spp. infections are gaining attention as a cause of serious zoonotic diseases, particularly affecting individuals with existing health issues like heart disease and immunosuppression.
- Diagnosing endocarditis linked to these infections is tough due to the tricky nature of Bartonella bacteria, necessitating specialized tests alongside standard blood cultures, which are often negative.
- A 74-year-old shepherd became the first documented case of infective endocarditis from Bartonella vinsonii subsp. berkhoffii, highlighting the importance of recognizing this pathogen in people with risk factors such as exposure to canids and underlying health conditions.
Unlabelled: Sonicating explanted prosthetic implants to physically remove biofilms is a recognized method for improving the microbiological diagnosis of prosthetic joint infection (PJI); however, chemical and enzymatic treatments have been investigated as alternative biofilm removal methods. We compared the biofilm dislodging efficacy of sonication followed by the addition of enzyme cocktails with different activity spectra in the diagnosis of PJI with that of the sonication of fluid cultures alone. Consecutive patients who underwent prosthesis explantation due to infection at our institution were prospectively enrolled for 1 year.
View Article and Find Full Text PDFAlthough the omicron variant of SARS-CoV-2 circulated intensely during the 2021-2022 season, many patients with severe acute respiratory disease tested negative for COVID-19. The aim of this study was to assess the presence of different respiratory viruses in deceased persons. The proportion of deceased persons with respiratory viral infections in the 2021-2022 season in Navarre, Spain, was estimated considering all deaths caused by confirmed COVID-19 according to the epidemiological surveillance and the results of multiplex PCR tests for respiratory viruses performed in a sample of deceased persons with a cause of death other than COVID-19.
View Article and Find Full Text PDFEffectiveness of Nirsevimab Immunoprophylaxis Administered at Birth to Prevent Infant Hospitalisation for Respiratory Syncytial Virus Infection: A Population-Based Cohort Study.
Vaccines (Basel)
April 2024
Article Synopsis
- Respiratory syncytial virus (RSV) is a common cause of hospitalization in newborns, but the risk decreases with age, prompting the use of nirsevimab for prevention in infants during their first RSV season.
- A study conducted in Navarre, Spain, showed that nirsevimab significantly reduced RSV hospitalizations, with a 88.7% effectiveness rate in infants who received the immunization at birth compared to those who did not.
- Immunizing infants born between October and December 2023 was found to prevent one hospitalization for every 15.3 infants immunized, suggesting that a strategy for immunization during RSV seasons could greatly reduce pediatric hospital admissions.