Disparities in Emergency Department Naloxone and Buprenorphine Initiation.

Introduction: Prescribing of buprenorphine and naloxone in the emergency department (ED) has been shown to be an effective intervention. The purpose of this study was to determine the frequency of prescribing of naloxone and buprenorphine and the sub-groups that may be more or less likely to receive treatment.

Methods: We used a national electronic health record database to identify patients with opioid poisoning or overdose presenting between January 2019-December 2021.

Initiation of Medication for Alcohol Use Disorder for Inpatients with Alcohol Withdrawal Syndromes.

Objective: Medications for alcohol use disorder (MAUD) are thought to be underused in the United States. This study reviewed data from a national database to determine the frequency of prescribing MAUD for patients admitted to the hospital or discharged with alcohol withdrawal syndromes (AWS).

Method: We searched for hospital admissions from 2019 to 2021 in the Epic Cosmos database associated with an active diagnosis of AWS.

Safety of induction at standard doses of buprenorphine for inpatients with opioid use disorder.

Unlabelled: Patients with opioid use disorder (OUD) are commonly admitted to various inpatient services where treatment can be started. The typical initiation of buprenorphine involves delay of treatment until withdrawal symptoms occur, however, those symptoms may interfere with other medical therapy. The purpose of this study was to evaluate the safety and efficacy of initiation of buprenorphine for inpatients with OUD.

Improving Timeliness of Antibiotic Administration Using a Provider and Pharmacist Facing Sepsis Early Warning System in the Emergency Department Setting: A Randomized Controlled Quality Improvement Initiative.

Objectives: Results of pre-post intervention studies of sepsis early warning systems have been mixed, and randomized clinical trials showing efficacy in the emergency department setting are lacking. Additionally, early warning systems can be resource-intensive and may cause unintended consequences such as antibiotic or IV fluid overuse. We assessed the impact of a pharmacist and provider facing sepsis early warning systems on timeliness of antibiotic administration and sepsis-related clinical outcomes in our setting.

Nicotine Patch Prescription Fulfillment Rates for Emergency Department Patients.

Introduction: Smoking cessation has significant health benefits, and the emergency department (ED) can be an important venue for smoking cessation counseling. Nicotine replacement therapy with transdermal patches has been shown to be associated with smoking cessation in a variety of studies. This study evaluated fulfillment rates for prescriptions for nicotine replacement transdermal patches (NRT-P) from the ED.