Publications by authors named "C El-Hayek"

People with a history of injecting drug use are a priority for eliminating blood-borne viruses and sexually transmissible infections. Identifying them for disease surveillance in electronic medical records (EMRs) is challenged by sparsity of predictors. This study introduced a novel approach to phenotype people who have injected drugs using structured EMR data and interactive human-in-the-loop methods.

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Introduction: Digitized patient progress notes from general practice represent a significant resource for clinical and public health research but cannot feasibly and ethically be used for these purposes without automated de-identification. Internationally, several open-source natural language processing tools have been developed, however, given wide variations in clinical documentation practices, these cannot be utilized without appropriate review. We evaluated the performance of four de-identification tools and assessed their suitability for customization to Australian general practice progress notes.

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Article Synopsis
  • This study investigates trends in hepatitis C virus (HCV) incidence among primary care patients over time to assess public health strategies for HCV elimination.
  • Researchers analyzed data from 6711 patients, identifying 210 new HCV infections and calculating an overall incidence rate of 1.1 per 100 person-years, with higher rates in patients prescribed opioid-related pharmacotherapy.
  • The findings indicate a decline in HCV incidence from 2009 to 2020, suggesting improvements in public health efforts, particularly with increased access to direct-acting antiviral (DAA) therapy.
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Article Synopsis
  • The study aimed to evaluate trends in hepatitis C virus (HCV) testing and methods for diagnosing individuals, focusing on primary care clinics in Victoria, Australia, from 2009 to 2019.
  • Over the period, 44,889 HCV antibody tests were conducted, showing a 6% annual increase in testing, although the positive test yield dropped significantly from 21% in 2009 to 9% in 2019.
  • The findings suggest that while testing strategies are effective in diagnosing HCV among people who inject drugs, more extensive testing efforts are necessary to meet HCV elimination targets in Australia.
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