Uncompacted lamellae in three patients with POEMS syndrome.

Three patients with POEMS syndrome were studied: two of them had myeloma, whereas the third had M protein without myeloma. Peripheral nerve biopsies showed no deposits of anti-Ig sera at direct immunopathological examination. Ultrastructural study revealed myelino-axonal degeneration in all three cases.

IgM demyelinative neuropathy with amyloidosis and biclonal gammopathy.

A 59-year-old man developed a sensorimotor neuropathy of the upper and lower limbs, associated with a biclonal gammopathy, within the space of a few months. Each of two paraproteins was coupled with a distinct IgM kappa IgG lambda light chain. Examination of a nerve biopsy specimen by electron microscopy revealed a demyelinative process with a widening of the interlaminar space in the myelin sheath, as well as deposits of amyloid substance between nerve fibers.

[Centrosomatic tuberculous vertebral osteitis. General review apropos of 4 cases].

Defined by the localisation of tuberculous infection in the vertebral body, centrosomatic tuberculous vertebral osteitis, which is rarer than Pott's spondylodiscitis, is more frequently seen in the cases of multifocal tuberculosis occurring preferentially in male black African immigrants approximately 30 years of age. Central area destruction, which has been the initial and pathognomonic radiological sign since its description by Calve and Galland , may progress towards wedging of the vertebral body, and even to its complete disappearance, accompanied by reactive osteocondensation . Infection from this particular localisation of vertebral tuberculosis may spread via arterial branches posterior to the vertebral bodies.