Publications by authors named "C Eduardo Vallejos"

The Scottish Patients at Risk of Re-Admission and Admission (SPARRA) score predicts individual risk of emergency hospital admission for approximately 80% of the Scottish population. It was developed using routinely collected electronic health records, and is used by primary care practitioners to inform anticipatory care, particularly for individuals with high healthcare needs. We comprehensively assess the SPARRA score across population subgroups defined by age, sex, ethnicity, socioeconomic deprivation, and geographic location.

View Article and Find Full Text PDF

Emergency admissions (EA), where a patient requires urgent in-hospital care, are a major challenge for healthcare systems. The development of risk prediction models can partly alleviate this problem by supporting primary care interventions and public health planning. Here, we introduce SPARRAv4, a predictive score for EA risk that will be deployed nationwide in Scotland.

View Article and Find Full Text PDF
Article Synopsis
  • - The study examined how genetic variations in the CYP2D6 gene and resulting endoxifen levels affect breast cancer outcomes in patients taking tamoxifen.
  • - Conducted with 113 patients with advanced hormone receptor-positive breast cancer, it compared those with poor CYP2D6 metabolism to those with normal or intermediate metabolism regarding progression-free survival (PFS).
  • - Results showed no significant relationship between CYP2D6 status, endoxifen concentrations, and PFS, possibly due to the small sample size and issues with sample collection in the trial.
View Article and Find Full Text PDF

The efficiency of CO flux in the leaf is hindered by a several structural and biochemical barriers which affect the overall net photosynthesis. However, the dearth of information about the genetic control of these features is limiting our ability for genetic manipulation. We performed a comparative analysis between three-week-old plants of a Mesoamerican and an Andean cultivar of at variable light and CO levels.

View Article and Find Full Text PDF