Two cases of metformin-associated lactic acidosis in post-operative period in emergency department: time to be aware-case reports.

Background: Diabetic patients on metformin therapy may be vulnerable to lactic acidosis during acute illness. This is particularly true since the comorbid conditions among patients with diabetes and the frequent use of renin-angiotensin system blockers increase the risk of renal dysfunction.

Case Description: We present two cases of metformin-associated lactic acidosis (MALA) occurred after abdominal surgery.

Biocompatibility and inflammatory response of silver tungstate, silver molybdate, and silver vanadate microcrystals.

Silver tungstate (α-AgWO), silver molybdate (β-AgMoO), and silver vanadate (α-AgVO) microcrystals have shown interesting antimicrobial properties. However, their biocompatibility is not yet fully understood. Cytotoxicity and the inflammatory response of silver-containing microcrystals were analyzed in THP-1 and THP-1 differentiated as macrophage-like cells, with the alamarBlue™ assay, flow cytometry, confocal microscopy, and ELISA.

Extracellular lipids of Candida albicans biofilm induce lipid droplet formation and decreased response to a topoisomerase I inhibitor in dysplastic and neoplastic oral cells.

Objective: Some microorganisms, i.e., Candida albicans, have been associated with cancer onset and development, although whether the fungus promotes cancer or whether cancer facilitates the growth of C.

Disclosing the Biocide Activity of α-AgCuWO (0 ≤ ≤ 0.16) Solid Solutions.

In this work, α-AgCuWO (0 ≤ ≤ 0.16) solid solutions with enhanced antibacterial (against methicillin-resistant ) and antifungal (against ) activities are reported. A plethora of techniques (X-ray diffraction with Rietveld refinements, inductively coupled plasma atomic emission spectrometry, micro-Raman spectroscopy, attenuated total reflectance-Fourier transform infrared spectroscopy, field emission scanning electron microscopy, ultraviolet-visible spectroscopy, photoluminescence emissions, and X-ray photoelectron spectroscopy) were employed to characterize the as-synthetized samples and determine the local coordination geometry of Cu cations at the orthorhombic lattice.

Inactivation of SARS-CoV-2 by a chitosan/α-AgWO composite generated by femtosecond laser irradiation.

In the current COVID-19 pandemic, the next generation of innovative materials with enhanced anti-SARS-CoV-2 activity is urgently needed to prevent the spread of this virus within the community. Herein, we report the synthesis of chitosan/α-AgWO composites synthetized by femtosecond laser irradiation. The antimicrobial activity against Escherichia coli, Methicilin-susceptible Staphylococcus aureus (MSSA), and Candida albicans was determined by estimating the minimum inhibitory concentration (MIC) and minimal bactericidal/fungicidal concentration (MBC/MFC).