Publications by authors named "C E Urbani"

Objective: Pasireotide LAR (PAS-LAR) was released in Italy in 2017 to treat acromegaly patients resistant to SRLs (Somatostatin Receptors Ligands). The long-term follow-up data of PAS-LAR therapy in Italy are limited. This study aimed to evaluate the efficacy and safety of PAS-LAR in acromegaly.

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Article Synopsis
  • The study aimed to investigate how various patient, disease, and treatment-related factors affect the likelihood of achieving long-term control of acromegaly, a hormonal disorder.
  • Data from 1546 patients treated with pegvisomant were analyzed over a 10-year period, focusing on baseline IGF-1 levels and other factors through comprehensive statistical analysis.
  • Key findings indicated that lower baseline IGF-1 levels (especially <300 µg/L) were strongly associated with improved long-term control of acromegaly, while factors such as age, sex, BMI, and pegvisomant dosage were not significant predictors.
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We study a two-layer energy balance model that allows for vertical exchanges between a surface layer and the atmosphere. The evolution equations of the surface temperature and the atmospheric temperature are coupled by the emission of infrared radiation by one level, that emission being partly captured by the other layer, and the effect of all non-radiative vertical exchanges of energy. Therefore, an essential parameter is the absorptivity of the atmosphere, denoted εa.

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Objectives: To explore the role of conventional X-ray imaging in detecting vertebral fractures (VFs) in patients with acromegaly, both at diagnosis of disease and at the last clinical visit. The risk factors for VFs were also evaluated.

Design And Methods: A retrospective cohort study was conducted on 60 consecutive patients with acromegaly, in a tertiary referral centre.

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Background: There are many aesthetic treatments aimed at combating aging. In the most common and frequently used ones there are often side effects, albeit minor ones. However, sometimes it is necessary to use medications before or after treatments.

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