Publications by authors named "C E Silvera"

Article Synopsis
  • Age-related issues like sarcopenia lead to physical disabilities, and the study focuses on changes in neurotrophic factors (BDNF and NT-4) and muscarinic signaling at neuromuscular junctions in aging rats compared to young ones.
  • The research found imbalances in several critical proteins associated with neurotransmission pathways, including alterations in receptor expression and reduced levels of specific channels, while other aspects remained stable.
  • The study suggests that these signaling pathways could potentially be adjusted to counteract age-related negative changes, warranting further research to improve neuromuscular function and enhance the quality of life for older adults.
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Background: Transactional sex relationships (TSRs) create financial and emotional support for men and women, as well as an increased sexual risk. Studies have reported high HIV and STI transmission rates among young women in transactional sex relationships. However, little is known about TSR prevalence in Jamaica and risky sexual practices among participants.

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Purpose: Identifying clinically relevant comorbidities and their effect on health-related quality of life (HRQoL) outcomes among men with advanced prostate cancer (APC) can inform patient care and improve outcomes; however, this is poorly understood. The aim of this observational study was to examine the prevalence of comorbidities, and the relationship of comorbidity burden to HRQoL and other patient-reported outcomes (PROs) among men with APC.

Methods: Participants were 192 men (average age 68.

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Identifying clinically relevant comorbidities and their effect on health-related quality of life (HRQoL) outcomes among men with advanced prostate cancer (APC) can inform patient care and improve outcomes; however, this is poorly understood. The aim of this observational study was to examine the prevalence of comorbidities, and the relationship of comorbidity burden to HRQoL and other patient-reported outcomes (PROs) among men with APC. Participants were 192 men (average age 68.

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Article Synopsis
  • * It involves a trial called My Well-Being Guide, which is a digital health intervention based on cognitive-behavioral stress management, aimed at lowering depressive symptoms over seven weeks.
  • * The study will assess effectiveness and implementation within two health systems, involving over 4,500 cancer patients and evaluating outcomes at multiple time points.
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