Publications by authors named "C E Scantlebury"
Exploring species seroprevalence and risk factors for seropositivity in The Gambia's working equid population: Baseline analysis of the Tackling Histoplasmosis project dataset.
Front Vet Sci
September 2024
Article Synopsis
- - The study aimed to determine the prevalence of antibodies to equine epizootic lymphangitis (EL) in horses and donkeys in rural Gambia and identify risk factors for seropositivity.
- - A total of 555 equids were tested, revealing a seroprevalence of 79.9% in horses and 46.7% in donkeys, with factors like age, sex, and season impacting these rates.
- - Two models showed that female horses and those from rainy season samples had higher odds of seropositivity, while younger horses and those involved in firewood transportation had lower odds.
Robust surveillance of species is warranted in endemic regions, including investigation of community-level transmission dynamics. This cross-sectional study explored anti- antibody seroprevalence and risk factors for exposure in a general population in Upper River Region (URR), The Gambia. Study participants were recruited (December 2022-March 2023) by random household sampling across 12 Enumeration Areas (EAs) of URR.
View Article and Find Full Text PDFUnlabelled: var (HCF) is a dimorphic fungus that causes epizootic lymphangitis in equids. Current diagnostic approaches, including culture, microscopy, and clinical presentation, lack speed, sensitivity, and specificity when diagnosing clinical cases. In this study, equine blood and pus samples on Whatman FTA cards from Senegal ( = 3), The Gambia ( = 19), Ethiopia ( = 16), and Mali ( = 13) were tested using a real-time PCR (qPCR) protocol.
View Article and Find Full Text PDFBackground: Inclusion of in the World Health Organization's first Fungal Priority Pathogens List under "high-priority" fungal species highlights the need for robust surveillance of spp. in endemic and underrepresented regions. Despite increasing reports of histoplasmosis in Africa, data on the burden of this fungal disease are sparse in The Gambia.
View Article and Find Full Text PDFEvidence of Histoplasma capsulatum seropositivity and exploration of risk factors for exposure in Busia county, western Kenya: Analysis of the PAZ dataset.
PLoS Negl Trop Dis
May 2023
Article Synopsis
- - The study investigated the presence of antibodies against
- Histoplasma capsulatum
- in the general population of Busia County, Kenya, finding a
- seroprevalence of 15.5%
- among 670 participants.
- - Results indicated that individuals with household rats and younger age groups (15-24 years) were at significantly
- higher risk
- for seropositivity, highlighting potential environmental and demographic risk factors for exposure.
- - The findings establish a
- baseline for future research
- on Histoplasma exposure in the area and emphasize the need for further investigation into the complex interplay of factors influencing the disease's epidemiology.