Publications by authors named "C E Remondegui"
In 2005 a universal vaccination program against hepatitis A was introduced in Argentina. Nevertheless, there are still some unvaccinated marginal population groups. There are no data about the seroprevalence of hepatitis E in the northern region of Argentina mainly because of lack of awareness of this emergent pathogen.
View Article and Find Full Text PDFBackground: The genetic diversity of persistent infectious agents, such as HHV-8, correlates closely with the migration of modern humans out of East Africa which makes them useful to trace human migrations. However, there is scarce data about the evolutionary history of HHV-8 particularly in multiethnic Latin American populations.
Objectives: The aims of this study were to characterize the genetic diversity and the phylogeography of HHV-8 in two distant geographic regions of Argentina, and to establish potential associations with pathogenic conditions and the genetic ancestry of the population.
Article Synopsis
- * In a study of 124 relatives of HTLV-1 infected individuals, 75% tested seronegative for the virus, with significant associations found between seronegative status and factors like being male, younger age, and having sensory/autonomic symptoms.
- * The findings suggest that HTLV-1 cases may be underestimated globally, and highlight the need for improved diagnostic algorithms that incorporate both serological and molecular testing to identify HTLV-1 infections more accurately.
HTLV-1 proviral load (pVL) in peripheral blood mononuclear cell (PBMCs) is proposed as a marker of disease progression but its role still remains controversial. The aim of this study was to evaluate the levels of HTLV-1 pVL in symptomatic patients and asymptomatic HTLV-1 carriers. In this cross-sectional study the pVL was measured by Real Time PCR in 102 asymptomatic carriers and 22 symptomatic patients (5ATLL, 15 TSP and 2 uveitis).
View Article and Find Full Text PDFBackground: Molecular and epidemiological studies of transmission routes and risk factors for infection by HTLV-1 are extremely important in order to implement control measures, especially because of the high prevalence of HTLV-1 in several regions of the world. San Salvador de Jujuy, Northwest Argentina, is a highly endemic area for HTLV-1 and foci of tropical spastic paraparesis/HTLV-1-associated myelopathy.
Objective: To gain further insight into the role of intrafamilial transmission of HTLV-1 in a highly endemic region in Argentina.