Publications by authors named "C E Pini"
Int J Mol Sci
November 2024
Article Synopsis
- The review explores how polyunsaturated fatty acids (PUFAs) are linked to various mental health disorders including dementia, schizophrenia, and anorexia nervosa by analyzing multiple types of studies.
- Evidence gathered indicates that PUFAs, especially ALA, EPA, and DHA, have neuroprotective properties that can improve brain function and behavior.
- A decrease in these fatty acids has been observed in populations with mental health disorders, suggesting that PUFA supplementation could serve as a promising treatment to help combat neuronal degeneration.
Cancer Imaging
November 2024
Article Synopsis
- SUVmax is a commonly used but limited parameter in assessing malignant lung nodules, with other metrics like lean body mass-adjusted values potentially offering more reliability.
- A study of 567 patients with suspected lung tumors showed that 91% had primary lung tumors, predominantly adenocarcinomas, yet SUVmax struggled to differentiate between benign and malignant lesions effectively.
- Survival analysis indicated that while SUVmax correlated with factors like overall survival and tumor characteristics, it lacked independent prognostic value, raising doubts about its sole reliance in clinical settings.
J Clin Med
September 2024
Article Synopsis
- Disease recurrence and resistance to radioiodine therapy pose significant challenges in managing differentiated thyroid cancer, particularly in patients with the TENIS syndrome, characterized by elevated thyroglobulin levels but negative radioiodine scans.
- A systematic review and meta-analysis evaluated the effectiveness of nuclear imaging, specifically [F]FDG PET/CT, on detecting thyroid cancer recurrence in TENIS patients, finding that it has a sensitivity of 87% and specificity of 76%.
- The study highlights the importance of [F]FDG PET/CT in guiding treatment decisions, especially as new radiopharmaceuticals continue to emerge for better detection of RAI-refractory cancer.
