Tracing the path of disruption: C isotope applications in traumatic brain injury-induced metabolic dysfunction.

Cerebral metabolic dysfunction is a critical pathological hallmark observed in the aftermath of traumatic brain injury (TBI), as extensively documented in clinical investigations and experimental models. An in-depth understanding of the bioenergetic disturbances that occur following TBI promises to reveal novel therapeutic targets, paving the way for the timely development of interventions to improve patient outcomes. The C isotope tracing technique represents a robust methodological advance, harnessing biochemical quantification to delineate the metabolic trajectories of isotopically labeled substrates.

A giant foramen of Vesalius: case report.

Anatomical variations identified at the skull base can result in challenges to the clinician. For example, the anatomy of the foramen ovale and its neighboring structures is critical knowledge for the surgeon who performs transcutaneous approaches to the foramen ovale for treating patients with trigeminal neuralgia. One nearby structure that can compound invasive procedures and potentially result in complications is the foramen of Vesalius.

Giant dural arteriovenous fistula in an infant.

Dural arteriovenous fistulas (dAVFs) are commonly encountered by the neurosurgeon. Herein, we present a case illustration of an infant presenting with an extremely large fistula that took up a significant part of the intracranial volume. A one-month-old female presented with irritability and failure to thrive.

'Haste makes waste': The tradeoff between walking speed and target-stepping accuracy.

Background: When environmental conditions require accurate foot placement during walking (e.g., on a rough path), we typically walk slower to avoid tripping, slipping or stumbling.

A Re-Appraisal of the Effect of Amplitude on the Stability of Interlimb Coordination Based on Tightened Normalization Procedures.

The stability of rhythmic interlimb coordination is governed by the coupling between limb movements. While it is amply documented how coordinative performance depends on movement frequency, theoretical considerations and recent empirical findings suggest that interlimb coupling (and hence coordinative stability) is actually mediated more by movement amplitude. Here, we present the results of a reanalysis of the data of Post, Peper, and Beek (2000), which were collected in an experiment aimed at teasing apart the effects of frequency and amplitude on coordinative stability of both steady-state and perturbed in-phase and antiphase interlimb coordination.